Nucleofill Treatments in London
Transform your skin with advanced Nucleofill treatments at our premier Aesthetic Clinic in central London. This revolutionary injectable treatment harnesses the power of PDRN (salmon DNA) to deliver exceptional skin rejuvenation results. Our expert practitioners utilise this cutting-edge skin booster to stimulate collagen production, enhance skin hydration, and restore your natural radiance from the cellular level.




Thousands of satisfied customers

Nucleofill Treatments Cost: Pricing Overview in London
Our Nucleofill pricing reflects the premium quality and expertise you receive at our central London clinic:
Single Treatment Sessions:
- Face treatment: £450-£650
- Under-eye area: £350-£450
- Neck and décolletage: £400-£550
- Hands: £300-£400
Treatment Packages:
- Three-session face package: £1,200-£1,750
- Combined face and neck package: £750-£950 per session
- Customise your treatment plan with our practitioners for optimal results
Investment in Nucleofill treatments provides long-lasting improvements to skin texture, firmness, and overall complexion. Results can be seen progressively over several weeks, making this injectable solution an exceptional value for comprehensive skin repair and regeneration.
Before and After Nucleofill Treatment
Nucleofill delivers remarkable transformation in skin condition and appearance. Patients typically notice:
Immediate Effects (Within 48-72 hours):
- Enhanced skin hydration and plumpness
- Improved skin texture and smoothness
- Subtle lifting effect
Progressive Results (2-8 weeks):
- Significant reduction in fine lines and wrinkles
- Increased collagen and elastin production
- Enhanced skin elasticity and firmness
- Improved cellular turnover and regeneration
- Brighter, more youthful skin appearance
Long-term Benefits (3-6 months):
- Sustained collagen production stimulation
- Deep hydration at molecular level
- Reduced appearance of acne scars and depressed scars
- Overall improvement in skin health and resilience
The regenerative properties of PDRN continue working long after treatment, with many patients experiencing ongoing improvements in their overall skin quality and complexion.
What is Nucleofill?
Nucleofill represents a breakthrough in non-surgical skin rejuvenation, utilising polynucleotide chains derived from salmon to promote natural skin repair processes. This innovative skin booster contains high concentration of polynucleotides that work at the cellular level to regenerate skin cells and stimulate natural healing mechanisms.
Key Components:
- PDRN (Polydeoxyribonucleotide): The active molecule that triggers cellular regeneration
- Nucleotide complexes that support DNA repair
- Hydrating properties that bind water molecules for lasting moisture
- Anti-inflammatory compounds that minimise irritation
Nucleofill works by delivering salmon DNA directly into the skin, where it acts as a biological stimulant. The polynucleotide chains stimulate collagen synthesis, enhance fibroblast activity, and promote tissue repair. This holistic approach to skin rejuvenation addresses multiple signs of ageing simultaneously, from fine lines to loss of hydration.
The treatment specifically targets damaged skin caused by UV rays, pollution, and oxidative stress, helping to protect the skin against future environmental damage whilst promoting skin repair from within.

Nucleofill Process: Step by Step
Our Nucleofill treatment follows a precise protocol to ensure optimal results and patient comfort:
Pre-Treatment Consultation (15-20 minutes):
- Comprehensive skin assessment
- Discussion of your skin condition goals
- Medical history review
- Treatment plan customisation
- Pre-treatment photography
Treatment Procedure (30-45 minutes):
- Injection site cleansing and preparation
- Topical anaesthetic application if required
- Strategic injection placement using fine needles
- PDRN skin booster delivery to targeted areas
- Gentle massage to optimise product distribution
Post-Treatment Care:
- Temporary redness and mild swelling at the injection sites may occur
- Bruising may occur but typically resolves within a few days
- Specific aftercare instructions provided
- Follow-up appointment scheduled
Recovery Timeline: Most patients experience minimal downtime, with any redness and swelling subsiding within 24-48 hours. The injections work immediately to begin the regeneration process, though visible improvements develop progressively over the following weeks.

Benefits of Nucleofill
Nucleofill offers comprehensive advantages for various skin conditions and concerns:
Regenerative Benefits:
- Stimulates natural collagen production and fibroblast growth
- Enhances cellular repair mechanisms
- Promotes regeneration of healthy skin cells
- Supports natural anti-ageing processes
Aesthetic Improvements:
- Reduces fine lines and surface wrinkles
- Improves skin texture and smoothness
- Enhances skin elasticity and firmness
- Creates more even complexion and tone
- Delivers deep hydration for lasting plumpness
Treatment Versatility:
- Addresses acne scarring and textural irregularities
- Suitable for face, neck, hands, and décolletage
- Versatile treatment for multiple age groups
- Can complement other cosmetic procedures
Long-term Skin Health:
- Anti-inflammatory effect reduces skin sensitivity
- Protects against free radicals and environmental damage
- Supports skin’s natural molecular weight balance
- Promotes ongoing cell growth and renewal
The synergy between PDRN’s regenerative properties and the skin’s natural healing processes creates lasting improvements that continue developing long after treatment completion.

Our Nucleofill Treatments
Aesthetic Clinic offers specialised Nucleofill treatments tailored to your unique skin needs:
Facial Rejuvenation Package:
- Comprehensive face treatment targeting signs of ageing
- Focus on fine lines and wrinkles reduction
- Collagen stimulation for improved firmness
- Designed for skin rejuvenation and texture improvement
Targeted Area Treatments:
- Under-eye rejuvenation for delicate skin
- Neck and décolletage firmer skin treatment
- Hand rejuvenation for age-related changes
- Acne scars and textural improvement therapy
Combination Therapy Options:
- Nucleofill with complementary skin treatments
- Integration with other injectable procedures
- Customise treatment protocols for enhanced results
- Maintenance programmes for sustained benefits
Specialised Protocols:
- Sensitive skin adaptations
- Various skin conditions treatment approaches
- Seasonal skin preparation programmes
- Flawless complexion maintenance plans
Each treatment utilises the full potential of salmon DNA technology, ensuring Nucleofill offers the most effective skin rejuvenation experience possible.
Why Choose Us?
Aesthetic Clinic stands as London’s premier destination for Nucleofill treatments, offering unparalleled expertise and patient care:
Clinical Excellence:
- Highly trained practitioners specialising in injectable therapies
- Advanced understanding of PDRN technology and application
- Comprehensive knowledge of skin repair mechanisms
- Commitment to achieving youthful skin results
Treatment Quality:
- Premium Nucleofill products with optimal molecular weight
- Sterile, state-of-the-art treatment environment
- Personalised approach to each patient’s skin condition
- Focus on natural-looking, long-lasting results
Patient Experience:
- Thorough consultation process
- Clear treatment expectations and timeline
- Comprehensive aftercare support
- Minimise discomfort through expert technique
Safety Standards:
- Detailed pre-treatment assessment
- Risk minimisation protocols
- Post-treatment monitoring
- Clear guidance on blood-thinning medications and contraindications
Our central London location provides convenient access to world-class skin rejuvenation treatments, where rejuvenate meets expertise for exceptional patient outcomes.
Frequently Asked Questions
How long do Nucleofill results last?
Nucleofill results typically last 6-12 months, with the regenerative effects of PDRN continuing to improve skin quality even after this period. The stimulation of collagen production creates long-lasting improvements, whilst maintenance treatments can extend and enhance results. Individual longevity depends on skin condition, age, and lifestyle factors.
Is there any downtime after Nucleofill treatment?
Nucleofill requires minimal downtime, making it an ideal non-surgical option. Temporary redness and mild swelling may occur at injection sites, typically resolving within 24-48 hours. Some patients may experience slight bruising, which usually fades within a few days. Most individuals return to normal activities immediately following treatment.
Can Nucleofill be combined with other treatments?
Yes, Nucleofill works excellently in combination with other cosmetic procedures. It can be paired with dermal fillers, other skin boosters, or various skin treatments to create a comprehensive anti-ageing approach. Our practitioners will assess your needs and customise a treatment plan that maximises the synergy between different procedures for optimal skin rejuvenation results.
Who is suitable for Nucleofill treatment?
Nucleofill is suitable for adults seeking to improve skin texture, hydration, and firmness. It’s particularly effective for those with fine lines, acne scars, or general signs of ageing. However, treatment may not be suitable for pregnant or breastfeeding women, those with certain medical conditions, or individuals taking blood-thinning medications. A thorough consultation determines candidacy.
How many sessions are needed for optimal results?
Most patients achieve excellent results with 2-3 Nucleofill sessions, spaced 3-4 weeks apart. The injectable treatment builds cumulative benefits, with each session enhancing collagen synthesis and cellular repair. Maintenance treatments every 6-12 months help sustain the regenerative effects and continue promoting skin repair for lasting skin health improvements.